Pregnenolone vs DHEA-S: The Hormones Before the Hormones
In this episode, weโre diving into two of the most overlooked hormones in womenโs health: pregnenolone and DHEA-S โ the hormones before the hormones.
While estrogen, progesterone, and testosterone often get the spotlight, pregnenolone and DHEA play a foundational role in the hormone cascade and can significantly influence energy, metabolism, fertility, cycles, thyroid function and stress resilience. When these hormones become depleted or dysregulated, symptoms like fatigue, cycle irregularities, low libido, poor recovery, inflammation, brain fog, and hormone imbalances can follow.
A few things we chat about in this episode ๐๐๐
- What pregnenolone & DHEA do in your hormone cascade
- Why they sit at the root of estrogen, progesterone, and testosterone balance
- What low pregnenolone or DHEA can mean, even with โnormalโ labs
- How bottlenecks between pregnenolone & DHEA disrupt hormone balance
- How stress shifts pregnenolone into downstream hormone pathways
- How low DHEA impacts ovulation, cycles, and hormones
- The link between energy, mitochondria, and pregnenolone and DHEA production
- Why these hormones are often overlooked in standard testing and what that means for your results
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Important show links ๐๐๐
- Learn more about adrenal hormones in this week’s blog postย
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LISTEN TO THE FULL PODCAST EPISODE! ๐


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